Located on the southern tropical tip of Texas, South Padre Island has the Gulf of Mexico on the east and the Laguna Madre Bay on the west. Beautiful beaches, warm Gulf waters, fishing, boating, bird watching, shopping, and a diversity of year-round activities await. Breathtaking sunsets over the bay, night clubs and restaurants come alive with conversation, dining, music and dancing. Many restaurants will cook your catch! No matter what your interests, South Padre Island offers one of the most fantastic beach vacation destinations in the world. South Padre Island.